• 2000–present MDX mid-size (crossover SUV)
• 2006–present RDX compact (crossover SUV)
• 2013–2022 ILX (Subcompact executive sedan, successor to the Integra^[36])
• 2014–present TLX (Executive sedan, replaces TL and TSX)
• 2017–2022 NSX (Exotic sports car, successor to first generation NSX)
• 2017–present CDX sub-compact (Luxury CUV)

Discontinued models

• 2014–2020 RLX (Mid-size luxury executive sedan, replaces RL)
• 2009–2013 ZDX (crossover SUV, discontinued for 2014 model year due to low sales and a $50,000 pricetag)
• 2005–2011 CSX (compact sedan, replacement for the EL; only available in Canada, replaced by the ILX)
• 2003–2014 TSX (compact sports sedan, sport wagon, replaced by the TLX)
• 2002–2006 RSX (sports coupe, replaced by the TSX)
• 1997–2005 EL (compact sedan, replaced Integra sedan; only available in Canada, replaced by the CSX)
• 1997–1999, 2001–2003 CL (luxury coupe, discontinued after 2003 model year)
• 1996–2014 TL (mid-size sports sedan, replaced by the TLX)
• 1996–2012 RL (full-size sedan, discontinued after 2012 model year, replaced by the RLX)
• 1996–1999 SLX (SUV, rebadged Isuzu Trooper, replaced by the MDX; only available in the United States)
• 1992–1994 Vigor (mid-sized sedan, replaced by the TL)
• 1985–2001 Integra (sports coupe and sedan, replaced by the RSX and EL, revival planned for 2022)^[37]
• 1985–1995 Legend (luxury sedan and coupe, renamed RL for 1996 model year)